Well, not really, but The Great LINQ shows a usage of LINQ to Objects over a chemistry domain:

from atom in molecule.Atoms
where atom.Element == Element.Hydrogen
and atom.Bonds.Count == 1
from atom2 in atom.Bonds[0].FindAtom(a => a != atom && a.Element == Element.Oxygen)
where atom2.FindBonds(b => b != atom.Bonds[0]).Count == 1
select atom2.FindBonds(b => b != atom.Bonds[0])[0].FindAtom(a => a != atom2)